SMART Digest™ Kits

SMART Digest delivers simple, robust, reproducible and fast digestion of proteins 

The Thermo Scientific™ SMART Digest™ kits are designed for biopharmaceutical and proteomic applications that require highly reproducible, sensitive and fast analyses, often in high throughput workflows. They achieve this due to the optimized heat stable immobilized trypsin design.

Challenges for biopharmaceutical and protein research laboratories

The modern biopharmaceutical and protein research laboratory is tasked with providing high quality analytical
results, often in high-throughput, regulated environments. One of the key areas which affects these requirements
is sample preparation. Current technologies employed are subject to high levels of irreproducibility, poor sensitivity, and protracted methodologies that are not amenable to automation and often require 24 hours to achieve full digestion.

In order to meet the industry demands, analytical workflows need to provide:

• High reproducibility 
• High sensitivity
• High levels of data quality
• Compatibility with automation

The SMART Digest kit is simple to implement and satisfies the analytical workflow demands. It offers significant benefits over existing conventional in-solution digestion protocols.

• Significantly faster than in-solution digestion
• 3-step sample preparation protocol
• Higher throughput
• Ability to automate
• More reproducible than in-solution digestion
• Higher sensitivity