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Orbitrap LC-MS



Hybrid Orbitrap Mass Spectrometers

Thermo Scientific
Orbitrap Exploris 120
Orbitrap Exploris 120

Thermo Scientific
Orbitrap Exploris 240
Orbitrap Exploris 240

Thermo Scientific
Orbitrap Exploris 480
Orbitrap Exploris 480

Analyses

 

Targeted/non-targeted screening (MS)
Unknown Identification (MS)
Confirmation (MS/MS)
Absolute and Relative Quantitation (MS and/or MS2)

 

Ideal Applications

Forensic Toxicology
Clinical Research
Food & Environmental Safety Testing
Targeted/Semi Metabolomics
Pharmaceuticals

Proteomics
Protein Identification
Forensic Toxicology
Anti Doping
Food and Environmental Emerging Contaminant Testing
Metabolomics

Shotgun Proteomics
Metabolomics
TMT Multiplexing
Protein Identification
Host Cell Proteins
Biopharma
Label Free Quantification
Clinical & Translational Research

Max Resolution (FWHM) @ m/z 200

120 000

240 000

480 000

Mass Accuracy

< 1 ppm

< 1 ppm

< 1 ppm

Dynamic Range

 5 orders

5 orders

5 orders

Mass Range

m/z 40 – 3000

m/z 40 – 6000
Up to 8000 with BioPharma option

m/z 40 – 6000
Up to 8000 with BioPharma option

Scan Speed

Up to 22 Hz

Up to 22 Hz

Up to 40 Hz

Scan Functions

Full MS, Full MS/AIF, SIM, DIA, t-MS2, t-SIM/dd-MS2

Full MS, Full Ms/AIF, SIM, t-MS2, DIA, dd-MS2, Full MS/AIF NL/dd-MS2, Full MS/dd-MS2

Full MS, Full Ms/AIF, SIM, t-MS2, DIA, dd-MS2, Full MS/AIF NL/dd-MS2, Full MS/dd-MS2

Dissociation

In-source CID, HCD

In-source CID, HCD

In-source CID, HCD

Ion Sources

APCI/APPI Combination

APCI/APPI Combination
FAIMS Pro interface
EASY-Spray source
Nanospray source

APCI/APPI Combination
FAIMS Pro interface
EASY-Spray source
Nanospray source

Chromatography System recommendations

Vanquish Core
Vanquish Flex
Vanquish Duo
Transcend

Vanquish Flex
Vanquish Duo
Vanquish Horizon
Easy-nLC 1200
Ultimate 3000 nano

Vanquish Flex
Vanquish Duo
Vanquish Horizon
Easy-nLC 1200
Ultimate 3000 nano



Tribrid Orbitrap Mass Spectrometers

 Orbitrap ID-X Tribrid MS
Orbitrap ID-X   

Orbitrap Fusion Lumos Tribrid MS
Orbitrap Fusion Lumos

Orbitrap Eclipse Tribrid MS
Orbitrap Eclipse

Analyses

 

MS and/or MSn
Identification
Confirmation
Screening
Profiling
Target/Non Target Screening

 

Ideal Applications

Small Molecules characterization in metabolomics, Pharma candidates, Lipids

MultiOmics, ТМТ
Protein Identification
Intact/ Top-down proteomics
Protein Interactions Targeted Quantification

MultiOmics, ТМТ
Protein Identification,
Intact/ Top-down proteomics
Protein Interactions Targeted Quantification ,
Top-down mass spectrometry
Biotherapeutics

AcquireX Data Acquisition

Yes

Yes

Yes

Max Resolution (FWHM) @ m/z 200

500 000

500 000

500 000

Optional резолюция 1 M FWHM

No

Yes

Yes

Mass Acuracy

< 1 ppm

< 1 ppm

< 1 ppm

Dynamic Range

 5 orders

5 orders

5 orders

Mass Range

m/z 50 – 2000

m/z 200 – 6000
Up to 8000 with BioPharma option

m/z 200 – 6000
Up to 8000 with BioPharma option

Scan Speed

Up to 40 Hz

Up to 40 Hz

Up to 40 Hz

Scan Functions

Full MS, MSn, n= 1 do 10,  Full Ms/AIF, SIM, t-MSn, DIA, dd-MS2, dd-MSn, Full MS/AIF NL/dd-MS2, Full MS/dd-MSn

Full MS, MSn, n= 1 do 10,  Full Ms/AIF, SIM, t-MSn, DIA, dd-MS2, dd-MSn, Full MS/AIF NL/dd-MS2, Full MS/dd-MSn

Full MS, MSn, n= 1 do 10,  Full Ms/AIF, SIM, t-MSn, DIA, dd-MS2, dd-MSn, Full MS/AIF NL/dd-MS2, Full MS/dd-MSn

Ion Sources

APCI/APPI Combination
 

APCI/APPI Combination
FAIMS Pro interface
EASY-Spray source
Nanospray source

APCI/APPI Combination
FAIMS Pro interface
EASY-Spray source
Nanospray source

Chromatography System recommendations

Vanquish Horizon
Vanquish Duo
Transcend

Vanquish Horizon
Easy-nLC 1200
Ultimate 3000 nano

Vanquish Horizon
Easy-nLC 1200
Ultimate 3000 nano

 



Liquid Chromatography
Ion Chromatography
Gas Chromatography
Chromatography Sample Preparation
Chromatography Software
Chromatography Columns and Consumables
LC MS – Liquid Chromatography Mass Spectrometry
GC MS - Gas Chromatography Mass Spectrometry
IC-MS – Ion Chromatography Mass Spectrometry
ICP-MS – Inductively Coupled Plasma Mass Spectrometry
IRMS - Isotope ratio Mass spectrometry
GD-MS – Glow Discharge Mass Spectrometry
Process Mass Spectrometry
MS Software – Mass Spectrometry Software
Infrared Spectrometers and Microscopes FT-IR
Near Infrared Analyzers NIR
Raman Spectrometers and Microscopes
Portable Spectrometers for Identification
Bench Top NMR Spectrometers
UV-VIS Spectrophotometers
DIA – Complex analyzers
Pharamaceutical Testing Equipment
Laboratory Systems for Pure and UltraPure Water
Gas Generators
Laboratory Equipment

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